Carbon Oxygen Demand Standards
Aqua Solutions COD Standard 1,000 ppm Certified Solution (500ML)
COD Standard 1,000 ppm Certified Solution (500ML)
Apexbio Technology LLC Docosanol (Abreua) 661-19-8 10g
Docosanol Abreua (CAS 661-19-8) is a small-molecule inhibitor targeting herpes simplex virus (HSV) It is designed to inhibit viral entry processes thereby preventing HSV replication at the initial stage of infection Docosanol Abreua exerts its biological activity primarily through the inhibition of viral envelope fusion with host cell membranes In cell-based studies Docosanol Abreua demonstrates antiviral inhibition with an IC50 value typically in the range of approximately 2 5-5 M Based on these pharmacological properties Docosanol Abreua holds research potential in antiviral mechanism studies investigation of viral entry pathways and host pathogen interaction assays
Apexbio Technology LLC Amoxicillin 26787-78-0 10g
Amoxicillin (26787-78-0) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to disrupt bacterial cell wall biosynthesis thereby impairing peptidoglycan cross-linking and compromising cell wall integrity Amoxicillin exerts its biological activity primarily through inhibition of PBPs interfering with the processes critical to bacterial cell wall formation In in vitro studies Amoxicillin demonstrates inhibitory activity with IC50 values ranging from 0 1 to 5 g/mL depending on experimental conditions and organism susceptibility Based on these pharmacological properties Amoxicillin holds research potential in studies of bacterial infection mechanisms antimicrobial responses and resistance development
Apexbio Technology LLC Arbutin 497-76-7 10g
Arbutin (CAS 497-76-7) is a naturally occurring glycosylated hydroquinone primarily isolated from bearberry (Arctostaphylos uva-ursi) leaves It acts as a competitive inhibitor of tyrosinase an enzyme central to melanin biosynthesis thereby modulating pigment production in biological systems Arbutin is extensively studied in cellular and biochemical assays investigating melanogenesis oxidative stress and potential antimelanogenic therapies Its ability to regulate melanin synthesis has made it a valuable research tool in dermatology cosmetic science and pharmacological studies focused on hyperpigmentation and related disorders The compound should be stored in a sealed cool and dry environment to maintain stability
Apexbio Technology LLC Bismuth Subsalicylate 14882-18-9 10g
Bismuth subsalicylate (CAS 14882-18-9) is a small molecule compound clinically employed in the management of gastrointestinal disturbances including diarrhea heartburn indigestion and nausea Its pharmacological activity involves a dual mechanism the bismuth component exerts antimicrobial and protective effects on the gastrointestinal mucosa while the salicylate moiety inhibits intestinal prostaglandin synthesis thereby reducing inflammation and intestinal secretions Bismuth subsalicylate is utilized in biomedical research to investigate gastrointestinal barrier function host microbe interactions and inflammatory pathways relevant to digestive disorders
Apexbio Technology LLC Tioconazole 65899-73-2 10g
Tioconazole (65899-73-2) is a small-molecule inhibitor targeting the fungal cytochrome P450-dependent enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane stability and cellular integrity Tioconazole exerts its biological activity primarily through interference with ergosterol biosynthesis within fungal cell membranes In in vitro studies Tioconazole demonstrates inhibitory activity with MIC50 values below 3 12 mg/L for dermatophyte strains and below 9 mg/L for yeast species Based on these pharmacological properties Tioconazole holds research potential in the study of antifungal mechanisms and in vitro antifungal screening assays
Apexbio Technology LLC Metronidazole Benzoate 13182-89-3 10g
Metronidazole Benzoate (13182-89-3) is a small-molecule inhibitor targeting microbial DNA synthesis It is designed to inhibit nucleic acid synthesis processes thereby disrupting microbial cellular function Metronidazole Benzoate exerts its biological activity primarily through inhibition of nucleic acid synthesis and function within microbial cells In in vitro studies its efficacy is often quantified by IC50 values reflecting the concentration required to achieve half-maximal inhibition of microbial growth Based on these pharmacological properties Metronidazole Benzoate holds research potential in investigations of treatments for bacterial and protozoal infections
Apexbio Technology LLC Tamoxifen Citrate 54965-24-1 10g
Tamoxifen Citrate (CAS 54965-24-1) is a small-molecule antagonist targeting estrogen receptors (ER) It is designed to competitively bind ER thereby modulating estrogen-mediated signal transduction Tamoxifen Citrate exerts its biological activity primarily by inhibiting the transcriptional activity of estrogen-responsive genes leading to reduced synthesis of factors related to cell growth and angiogenesis In in vitro studies Tamoxifen Citrate demonstrates inhibition of cell proliferation with reported IC50 values typically ranging from 3 to 7 M depending on cell line and experimental conditions Based on these pharmacological properties Tamoxifen Citrate holds research potential in studies of estrogen receptor-dependent signaling pathways and anti-tumor strategies particularly in breast cancer models
Apexbio Technology LLC (-)-Tetramisole 16595-80-5 10g
(-)-Tetramisole is an immunomodulatory agent that stimulates nicotinic acetylcholine receptors leading to the activation of T-lymphocytes macrophages and phagocytic cells to enhance cell-mediated immune responses (-)-Tetramisole exerts its biological activity primarily through activation of nicotinic acetylcholine receptors Additionally it is utilized in the investigation of epigenetic regulation pathways involving lysine-specific demethylase 1 (LSD1) serving as a research tool to study chromatin modulation mechanisms and gene expression control Based on these pharmacological properties (-)-Tetramisole holds research potential in immunological signaling studies and tumor biology
Apexbio Technology LLC Methyl tridecanoate 1731-88-0 10g
Methyl tridecanoate (CAS 1731-88-0) is a small-molecule inhibitor targeting -amyloid protein aggregation and acetylcholinesterase (AChE) It is designed to moderately inhibit -amyloid aggregation and weakly inhibit AChE activity Methyl tridecanoate exerts its biological activity primarily through inhibition of -amyloid aggregation and AChE enzymatic function [No experimental model/cell line or IC50/EC50 reported ]Based on these pharmacological properties methyl tridecanoate holds research potential in neurodegenerative disease models and lipid metabolism studies
Apexbio Technology LLC Diphenylpyraline HCl 132-18-3 10g
Diphenylpyraline HCl (CAS 132-18-3) is a small molecule classified within the diphenylpiperidine group and functions as a first-generation antihistamine It acts by competitively inhibiting histamine H1 receptors thereby attenuating histamine-mediated cellular responses In addition to its antihistaminic activity diphenylpyraline exhibits anticholinergic properties influencing neurotransmitter regulation within the central and peripheral nervous systems This compound is widely utilized in the study of histaminergic and cholinergic pathways as well as for elucidating mechanisms underlying allergic reactions and central nervous system disorders
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10g
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
TARGETMOL CHEMICALS INC DESCHLOROCLOZAPINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Deschloroclozapine a metabolite of Clozapine is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM respectively. purity: 99%
Apexbio Technology LLC L-Acetylcarnitine (hydrochloride) 5080-50-2 10g
L-Acetylcarnitine (hydrochloride) (CAS 5080-50-2) an acetylated derivative of L-carnitine facilitates the mitochondrial uptake of acetyl-CoA supporting fatty acid oxidation and energy metabolism It enhances acetylcholine synthesis and contributes to membrane phospholipid and protein production In vitro L-acetylcarnitine reduces SKOV-3 ovarian cancer cell proliferation at higher concentrations without affecting CA-125 or nerve growth factor receptor expression In vivo studies demonstrate its rapid and sustained antidepressant-like activity in rodent models linked to epigenetic upregulation of mGlu2 (Grm2) receptors L-acetylcarnitine is utilized in research focusing on metabolism neurobiology and psychiatric disorders